Until the last decades, the appearance of distant organ metastases of malignant tumors meant unequivocally that the surgical treatment of the process would be not very promising. In these cases surgery was considered a proof of surgical thoughtlessness and senseless attempt. Nevertheless, in the clinical practice of the last decades more and more observations have proven that in certain tumor types and in certain organ metastases surgical intervention is indicated even in these cases. Surgery has resulted sometimes in a better quality of life, sometimes even in cure. In this monograph the Authors present their clinical experience of several decades combined with the data of the literature for those interested in this topic, in the hope that by doing so, they provide help also for the patients.